• Menopausal hormone therapy and breast cancer risk: effect modification by body mass through life 

      Sandvei, Marie Søfteland; Vatten, Lars Johan; Bjelland, Elisabeth Krefting; Eskild, Anne; Hofvind, Solveig; Ursin, Giske; Opdahl, Signe (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-06)
      It is not known whether increased breast cancer risk caused by menopausal hormone therapy (HT) depends on body mass patterns through life. In a prospective study of 483,241 Norwegian women aged 50–69 years at baseline, 7656 women developed breast cancer during follow-up (2006–2013). We combined baseline information on recalled body mass in childhood/adolescence and current (baseline) body mass index ...
    • Nephronectin is Correlated with Poor Prognosis in Breast Cancer and Promotes Metastasis via its Integrin-Binding Motifs 

      Steigedal, Tonje S.; Toraskar, Jimita; Redvers, Richard P.; Valla, Marit; Magnussen, Synnøve; Bofin, Anna M.; Opdahl, Signe; Lundgren, Steinar; Eckhardt, Bedrich L.; Lamar, John M.; Doherty, Judy; Hynes, Richard O.; Anderson, Robin L.; Svineng, Gunbjørg (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-11)
      Most cancer patients with solid tumors who succumb to their illness die of metastatic disease. While early detection and improved treatment have led to reduced mortality, even for those with metastatic cancer, some patients still respond poorly to treatment. Understanding the mechanisms of metastasis is important to improve prognostication, to stratify patients for treatment, and to identify new ...